node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDS04645.1 | SDT37074.1 | SAMN04490182_0608 | SAMN04490182_4327 | Molecular chaperone HscC. | FeS assembly scaffold apoprotein IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.960 |
SDS04645.1 | SDT48269.1 | SAMN04490182_0608 | SAMN04490182_4896 | Molecular chaperone HscC. | DnaJ like chaperone protein. | 0.846 |
SDS04645.1 | iscA | SAMN04490182_0608 | SAMN04490182_4326 | Molecular chaperone HscC. | Iron-binding apoprotein IscA; Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system; Belongs to the HesB/IscA family. | 0.642 |
SDS04645.1 | nfuA | SAMN04490182_0608 | SAMN04490182_1661 | Molecular chaperone HscC. | Fe/S biogenesis protein NfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.557 |
SDT37074.1 | SDS04645.1 | SAMN04490182_4327 | SAMN04490182_0608 | FeS assembly scaffold apoprotein IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Molecular chaperone HscC. | 0.960 |
SDT37074.1 | SDT48269.1 | SAMN04490182_4327 | SAMN04490182_4896 | FeS assembly scaffold apoprotein IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | DnaJ like chaperone protein. | 0.991 |
SDT37074.1 | SDT64702.1 | SAMN04490182_4327 | SAMN04490182_6114 | FeS assembly scaffold apoprotein IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Hypothetical chaperone protein. | 0.951 |
SDT37074.1 | dnaK | SAMN04490182_4327 | SAMN04490182_4521 | FeS assembly scaffold apoprotein IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.965 |
SDT37074.1 | hscA | SAMN04490182_4327 | SAMN04490182_4324 | FeS assembly scaffold apoprotein IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Chaperone protein HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. | 0.995 |
SDT37074.1 | iscA | SAMN04490182_4327 | SAMN04490182_4326 | FeS assembly scaffold apoprotein IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Iron-binding apoprotein IscA; Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system; Belongs to the HesB/IscA family. | 0.990 |
SDT37074.1 | nfuA | SAMN04490182_4327 | SAMN04490182_1661 | FeS assembly scaffold apoprotein IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Fe/S biogenesis protein NfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.986 |
SDT48269.1 | SDS04645.1 | SAMN04490182_4896 | SAMN04490182_0608 | DnaJ like chaperone protein. | Molecular chaperone HscC. | 0.846 |
SDT48269.1 | SDT37074.1 | SAMN04490182_4896 | SAMN04490182_4327 | DnaJ like chaperone protein. | FeS assembly scaffold apoprotein IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.991 |
SDT48269.1 | SDT48282.1 | SAMN04490182_4896 | SAMN04490182_4897 | DnaJ like chaperone protein. | Nucleotidyl transferase. | 0.813 |
SDT48269.1 | SDT48297.1 | SAMN04490182_4896 | SAMN04490182_4898 | DnaJ like chaperone protein. | Hypothetical protein. | 0.809 |
SDT48269.1 | SDT64702.1 | SAMN04490182_4896 | SAMN04490182_6114 | DnaJ like chaperone protein. | Hypothetical chaperone protein. | 0.827 |
SDT48269.1 | dnaK | SAMN04490182_4896 | SAMN04490182_4521 | DnaJ like chaperone protein. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.846 |
SDT48269.1 | hscA | SAMN04490182_4896 | SAMN04490182_4324 | DnaJ like chaperone protein. | Chaperone protein HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. | 0.846 |
SDT48269.1 | iscA | SAMN04490182_4896 | SAMN04490182_4326 | DnaJ like chaperone protein. | Iron-binding apoprotein IscA; Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system; Belongs to the HesB/IscA family. | 0.701 |
SDT48269.1 | lptD | SAMN04490182_4896 | SAMN04490182_4899 | DnaJ like chaperone protein. | LPS-assembly protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. | 0.719 |