STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ALP40860.1HAD-superfamily (subfamily IA) hydrolase. (227 aa)    
Predicted Functional Partners:
udk
Uridine/cytidine kinase.
 
 
  0.934
gsk
Inosine/guanosine kinase.
 
  
  0.925
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 0.919
purA2
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
 
 
  0.919
tdk
Thymidine kinase.
 
  
  0.918
cpdB
2', 3'-cyclic-nucleotide 2'-phosphodiesterase; Belongs to the 5'-nucleotidase family.
  
  
 0.916
nutA
Bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; Belongs to the 5'-nucleotidase family.
  
  
 0.913
ALP39633.1
Uridine phosphorylase.
  
 
  0.912
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
  0.911
nadD
Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
    
 0.910
Your Current Organism:
Aeromonas schubertii
NCBI taxonomy Id: 652
Other names: A. schubertii, ATCC 43700, Aeromonas hybridization group 12, CCUG 27820, CDC 2446-81, CECT 4240, CIP 103437, DSM 4882, Enteric Group 501, JCM 7373, LMG 9074, LMG:9074
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