Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
yibHSecretion protein HlyD; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (345 aa)    
Predicted Functional Partners:
yiaW
DNA repair ATPase.
 
   
 0.951
ALP42446.1
Outer membrane efflux protein.
 
 
 0.744
ALP39652.1
Membrane protein.
 
 
 0.696
macB2
Macrolide-specific ABC-type efflux carrier; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
  
 0.680
ALP39853.1
Hemolysin D.
 
     0.631
ALP40303.1
Membrane-fusion protein.
  
     0.602
tolC
Outer membrane channel protein.
  
 
 0.598
acrE
Acriflavin resistance protein A; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
     0.563
ALP42401.1
Secretion protein HlyD family protein.
  
     0.553
ALP42356.1
Multidrug ABC transporter permease.
 
  
 0.518
Your Current Organism:
Aeromonas schubertii
NCBI taxonomy Id: 652
Other names: A. schubertii, ATCC 43700, Aeromonas hybridization group 12, CCUG 27820, CDC 2446-81, CECT 4240, CIP 103437, DSM 4882, Enteric Group 501, JCM 7373, LMG 9074, LMG:9074
Server load: medium (48%) [HD]