STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
macAMacrolide-specific efflux protein MacA; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (384 aa)    
Predicted Functional Partners:
macB2
Macrolide-specific ABC-type efflux carrier; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
 
 
 0.996
ALP42446.1
Outer membrane efflux protein.
 
 
 0.963
ALP40305.1
Peptide ABC transporter permease.
 
 
 0.883
ALP40433.1
ABC transporter permease.
 
 
 0.880
bepE
RND transporter.
 
 
 0.685
ALP41312.1
Putative multidrug resistance protein.
 
 
 0.662
tolC
Outer membrane channel protein.
  
 
 0.659
cusA
Cation efflux system protein CusA; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
 
 0.658
ALP40885.1
Multidrug resistance protein.
 
 
 0.651
ALP41421.1
Acriflavin resistance plasma membrane protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
 
 0.636
Your Current Organism:
Aeromonas schubertii
NCBI taxonomy Id: 652
Other names: A. schubertii, ATCC 43700, Aeromonas hybridization group 12, CCUG 27820, CDC 2446-81, CECT 4240, CIP 103437, DSM 4882, Enteric Group 501, JCM 7373, LMG 9074, LMG:9074
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.