Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pepA-2Multifunctional aminopeptidase A; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. (502 aa)    
Predicted Functional Partners:
gshB
Glutathione synthetase; Belongs to the prokaryotic GSH synthase family.
   
 
 0.927
pepA
Cytosol aminopeptidase; Belongs to the peptidase M17 family.
  
  
 
0.925
pepN
Aminopeptidase N.
   
 0.925
pepB-2
Aminopeptidase B.
  
  
 
0.923
pepB
Aminopeptidase B; Probably plays an important role in intracellular peptide degradation.
  
  
 
0.922
ALP42048.1
Gamma-glutamyltranspeptidase.
     
 0.918
pepD
Aminoacyl-histidine dipeptidase.
   
 
 0.909
gshA
Glutamate--cysteine ligase; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
     
 0.904
aspC
Aromatic amino acid aminotransferase.
    
 0.819
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.814
Your Current Organism:
Aeromonas schubertii
NCBI taxonomy Id: 652
Other names: A. schubertii, ATCC 43700, Aeromonas hybridization group 12, CCUG 27820, CDC 2446-81, CECT 4240, CIP 103437, DSM 4882, Enteric Group 501, JCM 7373, LMG 9074, LMG:9074
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