STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rseAsigma-E factor negative regulatory protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic p [...] (194 aa)    
Predicted Functional Partners:
ALP43715.1
sigma-E factor regulatory protein RseB.
 
 
 0.999
rpoE
RNA polymerase sigma factor RpoE; Belongs to the sigma-70 factor family. ECF subfamily.
 
 
 0.992
ALP41263.1
DNA-directed RNA polymerase subunit sigma; Belongs to the sigma-70 factor family. ECF subfamily.
  
 
 0.940
ALP40581.1
Hypothetical protein.
 
 
 0.930
ALP41266.1
RNA polymerase sigma factor; Belongs to the sigma-70 factor family. ECF subfamily.
 
 
 0.924
ALP42710.1
sigma-E factor regulatory protein RseC.
 
  
 0.904
degS
Periplasmic serine peptidase DegS.
  
 
 0.881
degQ
DegQ serine protease; Belongs to the peptidase S1C family.
  
 
 0.878
sspB
Peptidase.
  
 
 
 0.853
ALP41666.1
Hypothetical protein.
   
    0.720
Your Current Organism:
Aeromonas schubertii
NCBI taxonomy Id: 652
Other names: A. schubertii, ATCC 43700, Aeromonas hybridization group 12, CCUG 27820, CDC 2446-81, CECT 4240, CIP 103437, DSM 4882, Enteric Group 501, JCM 7373, LMG 9074, LMG:9074
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