| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| edd | hmgCL | WL1483_2653 | WL1483_5008 | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. | hydroxymethylglutaryl-CoA lyase. | 0.756 |
| edd | leuA | WL1483_2653 | WL1483_3739 | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.808 |
| edd | pabC | WL1483_2653 | WL1483_274 | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. | 4-amino-4-deoxychorismate lyase. | 0.809 |
| edd | thrA | WL1483_2653 | WL1483_3647 | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. | Bifunctional aspartokinase I/homoserine dehydrogenase I; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.686 |
| folP | pabA | WL1483_3710 | WL1483_1346 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Para-aminobenzoate synthase glutamine amidotransferase component II. | 0.698 |
| folP | pabB | WL1483_3710 | WL1483_3744 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Para-aminobenzoate synthase, component I. | 0.632 |
| folP | pabC | WL1483_3710 | WL1483_274 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 4-amino-4-deoxychorismate lyase. | 0.943 |
| hmgCL | edd | WL1483_5008 | WL1483_2653 | hydroxymethylglutaryl-CoA lyase. | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. | 0.756 |
| hmgCL | ilvD | WL1483_5008 | WL1483_2083 | hydroxymethylglutaryl-CoA lyase. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.756 |
| hmgCL | pabC | WL1483_5008 | WL1483_274 | hydroxymethylglutaryl-CoA lyase. | 4-amino-4-deoxychorismate lyase. | 0.783 |
| hmgCL | thrA | WL1483_5008 | WL1483_3647 | hydroxymethylglutaryl-CoA lyase. | Bifunctional aspartokinase I/homoserine dehydrogenase I; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.685 |
| ilvD | hmgCL | WL1483_2083 | WL1483_5008 | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | hydroxymethylglutaryl-CoA lyase. | 0.756 |
| ilvD | leuA | WL1483_2083 | WL1483_3739 | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.989 |
| ilvD | pabC | WL1483_2083 | WL1483_274 | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 4-amino-4-deoxychorismate lyase. | 0.809 |
| ilvD | thrA | WL1483_2083 | WL1483_3647 | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | Bifunctional aspartokinase I/homoserine dehydrogenase I; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.686 |
| leuA | edd | WL1483_3739 | WL1483_2653 | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. | 0.808 |
| leuA | ilvD | WL1483_3739 | WL1483_2083 | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.989 |
| leuA | pabC | WL1483_3739 | WL1483_274 | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 4-amino-4-deoxychorismate lyase. | 0.783 |
| leuA | thrA | WL1483_3739 | WL1483_3647 | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | Bifunctional aspartokinase I/homoserine dehydrogenase I; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.763 |
| mltG | pabC | WL1483_202 | WL1483_274 | Hypothetical protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. | 4-amino-4-deoxychorismate lyase. | 0.792 |