Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
acrEAcriflavin resistance protein A; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (403 aa)    
Predicted Functional Partners:
bepE
RND transporter.
 0.998
ALP42446.1
Outer membrane efflux protein.
 
 0.986
ALP41421.1
Acriflavin resistance plasma membrane protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
 0.980
tolC
Outer membrane channel protein.
 
 0.978
ALP43748.1
AcrB/AcrD/AcrF family transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
 0.961
ALP39652.1
Membrane protein.
  
 0.943
macB2
Macrolide-specific ABC-type efflux carrier; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
 
 
 0.907
ALP41312.1
Putative multidrug resistance protein.
 
 
 0.830
ALP40885.1
Multidrug resistance protein.
 
 
 0.803
ALP39567.1
Hypothetical protein.
 
 0.796
Your Current Organism:
Aeromonas schubertii
NCBI taxonomy Id: 652
Other names: A. schubertii, ATCC 43700, Aeromonas hybridization group 12, CCUG 27820, CDC 2446-81, CECT 4240, CIP 103437, DSM 4882, Enteric Group 501, JCM 7373, LMG 9074, LMG:9074
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.