Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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Score
folBDihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (123 aa)    
Predicted Functional Partners:
ALP39598.1
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase.
 
 
 0.998
folP
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
 
 
 0.996
folK
7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase.
 
 
 0.992
folE
GTP cyclohydrolase I.
 
  
 0.961
ALP43525.1
7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase.
 
 
 0.928
ALP43509.1
Pteridine reductase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
    
 0.903
ALP40671.1
Alkaline phosphatase; Belongs to the alkaline phosphatase family.
     
 0.900
ALP41318.1
Alkaline phosphatase; Belongs to the alkaline phosphatase family.
     
 0.900
folC
Folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family.
  
  
 0.773
ALP41001.1
HAM1 protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
 
  
 0.719
Your Current Organism:
Aeromonas schubertii
NCBI taxonomy Id: 652
Other names: A. schubertii, ATCC 43700, Aeromonas hybridization group 12, CCUG 27820, CDC 2446-81, CECT 4240, CIP 103437, DSM 4882, Enteric Group 501, JCM 7373, LMG 9074, LMG:9074
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