| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ALP40462.1 | clpA | WL1483_1043 | WL1483_1216 | Hypothetical protein. | ATP-dependent Clp protease, ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | 0.751 |
| ALP40462.1 | dnaJ | WL1483_1043 | WL1483_3642 | Hypothetical protein. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.807 |
| ALP40462.1 | dnaK | WL1483_1043 | WL1483_830 | Hypothetical protein. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.882 |
| ALP40462.1 | grpE | WL1483_1043 | WL1483_3091 | Hypothetical protein. | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | 0.858 |
| ALP40462.1 | hscA | WL1483_1043 | WL1483_1117 | Hypothetical protein. | Chaperone protein HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. | 0.882 |
| ALP40462.1 | hslU | WL1483_1043 | WL1483_4251 | Hypothetical protein. | ATP-dependent protease ATP-binding subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.702 |
| ALP40462.1 | hslV | WL1483_1043 | WL1483_2546 | Hypothetical protein. | ATP-dependent protease subunit HslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.630 |
| ALP40462.1 | htpG | WL1483_1043 | WL1483_3770 | Hypothetical protein. | Heat shock protein 90; Molecular chaperone. Has ATPase activity. | 0.817 |
| ALP40462.1 | ibpA | WL1483_1043 | WL1483_501 | Hypothetical protein. | DNA gyrase subunit B; Belongs to the small heat shock protein (HSP20) family. | 0.808 |
| clpA | ALP40462.1 | WL1483_1216 | WL1483_1043 | ATP-dependent Clp protease, ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | Hypothetical protein. | 0.751 |
| clpA | dnaJ | WL1483_1216 | WL1483_3642 | ATP-dependent Clp protease, ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.807 |
| clpA | dnaK | WL1483_1216 | WL1483_830 | ATP-dependent Clp protease, ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.899 |
| clpA | grpE | WL1483_1216 | WL1483_3091 | ATP-dependent Clp protease, ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | 0.858 |
| clpA | hscA | WL1483_1216 | WL1483_1117 | ATP-dependent Clp protease, ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | Chaperone protein HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. | 0.882 |
| clpA | hslU | WL1483_1216 | WL1483_4251 | ATP-dependent Clp protease, ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | ATP-dependent protease ATP-binding subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.702 |
| clpA | hslV | WL1483_1216 | WL1483_2546 | ATP-dependent Clp protease, ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | ATP-dependent protease subunit HslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.630 |
| clpA | htpG | WL1483_1216 | WL1483_3770 | ATP-dependent Clp protease, ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | Heat shock protein 90; Molecular chaperone. Has ATPase activity. | 0.817 |
| clpA | ibpA | WL1483_1216 | WL1483_501 | ATP-dependent Clp protease, ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | DNA gyrase subunit B; Belongs to the small heat shock protein (HSP20) family. | 0.808 |
| clpB | dnaJ | WL1483_3946 | WL1483_3642 | ATP-dependent Clp protease, ATP-binding subunit ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.807 |
| clpB | dnaK | WL1483_3946 | WL1483_830 | ATP-dependent Clp protease, ATP-binding subunit ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.904 |
