STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ilvYDNA-binding transcriptional regulator IlvY; Belongs to the LysR transcriptional regulatory family. (294 aa)    
Predicted Functional Partners:
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
 
     0.759
ALP39583.1
LysR family transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
  
     0.711
ALP43058.1
LysR family transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
  
     0.706
ALP43416.1
LysR family transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
  
     0.639
ALP42960.1
Glycine cleavage operon activator, putative; Belongs to the LysR transcriptional regulatory family.
  
     0.620
ALP39871.1
Regulatory protein LysR; Belongs to the LysR transcriptional regulatory family.
  
     0.554
ALP42120.1
Regulatory protein; Belongs to the LysR transcriptional regulatory family.
  
     0.532
ALP39521.1
Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
  
     0.444
ALP40286.1
LysR family transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
  
     0.415
Your Current Organism:
Aeromonas schubertii
NCBI taxonomy Id: 652
Other names: A. schubertii, ATCC 43700, Aeromonas hybridization group 12, CCUG 27820, CDC 2446-81, CECT 4240, CIP 103437, DSM 4882, Enteric Group 501, JCM 7373, LMG 9074, LMG:9074
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