node1 | node2 | node1 annotation | node2 annotation | score |
A0A2C9JEV6 | A0A2C9JGI9 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 0.959 |
A0A2C9JEV6 | A0A2C9JGV2 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.921 |
A0A2C9JEV6 | A0A2C9JJ80 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Uncharacterized protein. | 0.941 |
A0A2C9JEV6 | A0A2C9JNJ2 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | PALP domain-containing protein. | 0.923 |
A0A2C9JEV6 | A0A2C9JT61 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Uncharacterized protein. | 0.923 |
A0A2C9JEV6 | A0A2C9JU61 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.973 |
A0A2C9JEV6 | A0A2C9JVS6 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 10-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily. | 0.924 |
A0A2C9JEV6 | A0A2C9K384 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | AdoHcyase_NAD domain-containing protein. | 0.946 |
A0A2C9JEV6 | A0A2C9K691 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. | 0.938 |
A0A2C9JEV6 | A0A2C9LBW0 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Uncharacterized protein. | 0.922 |
A0A2C9JGI9 | A0A2C9JEV6 | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.959 |
A0A2C9JGI9 | A0A2C9JGV2 | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.999 |
A0A2C9JGI9 | A0A2C9JJ80 | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | Uncharacterized protein. | 0.999 |
A0A2C9JGI9 | A0A2C9JNJ2 | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | PALP domain-containing protein. | 0.707 |
A0A2C9JGI9 | A0A2C9JU61 | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.952 |
A0A2C9JGI9 | A0A2C9JVS6 | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 10-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily. | 0.995 |
A0A2C9JGI9 | A0A2C9K384 | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | AdoHcyase_NAD domain-containing protein. | 0.475 |
A0A2C9JGI9 | A0A2C9K691 | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. | 0.989 |
A0A2C9JGI9 | A0A2C9LBW0 | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | Uncharacterized protein. | 0.996 |
A0A2C9JGV2 | A0A2C9JEV6 | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.921 |