A0A2C9JIN8 protein (Biomphalaria glabrata) - STRING interaction network

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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gene co-occurrence

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A0A2C9JIN8

Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1347 aa)

Predicted Functional Partners:

A0A2C9K212

0.949

A0A2C9M1W5

0.925

A0A2C9M5V3

0.893

A0A2C9KLI9

0.877

A0A2C9JHT8

0.867

A0A2C9JEQ9

0.848

A0A2C9KNI2

0.807

A0A2C9LLR8

0.807

A0A2C9KGR8

0.802

A0A2C9K949

0.799

Your Current Organism:

Biomphalaria glabrata

NCBI taxonomy Id: 6526
Other names: Australorbis glabratus, B. glabrata, Planorbis glabratus, bloodfluke planorb

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A2C9JEQ9	A0A2C9JIN8	Uncharacterized protein.	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.848
A0A2C9JHT8	A0A2C9JIN8	Uncharacterized protein.	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.867
A0A2C9JHT8	A0A2C9K212	Uncharacterized protein.	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.992
A0A2C9JHT8	A0A2C9K949	Uncharacterized protein.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.838
A0A2C9JHT8	A0A2C9KGR8	Uncharacterized protein.	DUF5595 domain-containing protein.	0.955
A0A2C9JHT8	A0A2C9KLI9	Uncharacterized protein.	FHA domain-containing protein.	0.897
A0A2C9JHT8	A0A2C9KNI2	Uncharacterized protein.	Uncharacterized protein.	0.928
A0A2C9JHT8	A0A2C9LLR8	Uncharacterized protein.	Uncharacterized protein.	0.965
A0A2C9JHT8	A0A2C9M1W5	Uncharacterized protein.	Uncharacterized protein.	0.990
A0A2C9JHT8	A0A2C9M5V3	Uncharacterized protein.	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.928
A0A2C9JIN8	A0A2C9JEQ9	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Uncharacterized protein.	0.848
A0A2C9JIN8	A0A2C9JHT8	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Uncharacterized protein.	0.867
A0A2C9JIN8	A0A2C9K212	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.949
A0A2C9JIN8	A0A2C9K949	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.799
A0A2C9JIN8	A0A2C9KGR8	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	DUF5595 domain-containing protein.	0.802
A0A2C9JIN8	A0A2C9KLI9	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	FHA domain-containing protein.	0.877
A0A2C9JIN8	A0A2C9KNI2	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Uncharacterized protein.	0.807
A0A2C9JIN8	A0A2C9LLR8	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Uncharacterized protein.	0.807
A0A2C9JIN8	A0A2C9M1W5	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Uncharacterized protein.	0.925
A0A2C9JIN8	A0A2C9M5V3	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.893

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Network Stats

number of nodes:

11

number of edges:

35

average node degree:

6.36

avg. local clustering coefficient:

0.832

expected number of edges:

11

PPI enrichment p-value:

2.69e-09

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0051231

Spindle elongation

9 of 18

3.68

15.08

2.98e-28

GO:0090307

Mitotic spindle assembly

9 of 29

3.47

14.26

5.19e-27

GO:0007018

Microtubule-based movement

11 of 206

2.71

12.55

5.19e-27

GO:0000070

Mitotic sister chromatid segregation

9 of 120

2.86

11.01

2.02e-22

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0008574

Plus-end-directed microtubule motor activity

9 of 44

3.29

13.54

5.17e-26

GO:0003777

Microtubule motor activity

11 of 183

2.76

12.96

1.74e-27

GO:0008017

Microtubule binding

11 of 499

2.32

9.35

2.16e-23

GO:0005524

ATP binding

11 of 10499

1.0

1.25

3.04e-09

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0072686

Mitotic spindle

9 of 48

3.25

13.33

1.06e-25

GO:0005876

Spindle microtubule

9 of 80

3.03

12.2

3.73e-24

GO:0005874

Microtubule

11 of 607

2.24

8.69

8.18e-23

GO:0005737

Cytoplasm

10 of 38115

0.4

0.3

0.0168

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:145257

Kinesin motor domain, conserved site, and Plus-end directed microtubule sliding

8 of 59

3.11

10.29

4.49e-20

CL:145259

Mixed, incl. Spindle elongation, and Microtubule depolymerization

7 of 45

3.17

9.5

2.02e-18

CL:145261

Mixed, incl. Spindle elongation, and Kinesin-like protein KIF15/KIN-12

6 of 37

3.19

8.03

1.45e-15

CL:145263

Mixed, incl. Spindle elongation, and Regulation of spindle assembly

4 of 20

3.28

5.06

6.25e-10

CL:145264

Mixed, incl. Spindle elongation, and Regulation of spindle assembly

3 of 12

3.38

3.6

3.15e-07

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map04144

Endocytosis

10 of 1052

1.96

5.82

1.83e-17

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-983189

Kinesins

10 of 164

2.77

11.77

1.15e-24

MAP-6811434

COPI-dependent Golgi-to-ER retrograde traffic

10 of 363

2.42

9.24

1.35e-21

MAP-8856688

Golgi-to-ER retrograde transport

10 of 467

2.31

8.44

1.08e-20

MAP-983231

Factors involved in megakaryocyte development and platelet production

10 of 531

2.25

8.04

2.89e-20

MAP-6811442

Intra-Golgi and retrograde Golgi-to-ER traffic

10 of 567

2.23

7.85

4.43e-20

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005876

Spindle microtubule

9 of 33

3.42

14.06

9.48e-27

GOCC:0015630

Microtubule cytoskeleton

10 of 944

2.01

6.12

9.42e-18

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0505

Motor protein

11 of 214

2.69

12.73

1.21e-27

KW-0067

ATP-binding

11 of 5170

1.31

2.29

7.38e-13

KW-0175

Coiled coil

10 of 10941

0.94

1.07

1.34e-07

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR047149

Kinesin-like protein KIF11-like

9 of 15

3.76

15.27

1.58e-28

IPR001752

Kinesin motor domain

11 of 160

2.82

13.34

7.21e-28

IPR036961

Kinesin motor domain superfamily

11 of 192

2.74

12.75

3.34e-27

IPR047241

Kinesin-like protein KIF11-like, kinesin motor domain

7 of 10

3.83

11.8

4.32e-22

IPR019821

Kinesin motor domain, conserved site

9 of 99

2.94

11.3

1.18e-22

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00129

Kinesin motor, catalytic domain. ATPase.

11 of 160

2.82

13.71

1.01e-28

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