STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A2C9K182DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (564 aa)    
Predicted Functional Partners:
A0A2C9M067
BRCT domain-containing protein.
   
 0.940
A0A2C9L992
XRCC1_N domain-containing protein.
   
 0.847
A0A2C9KGG5
Uncharacterized protein.
   
 0.836
A0A2C9JHQ7
DNA ligase.
  
 0.797
A0A2C9JPS9
FPG_CAT domain-containing protein.
   
 0.786
A0A2C9M6M2
Ku domain-containing protein.
    
 0.777
A0A2C9JTX9
DNA ligase.
  
 0.741
A0A2C9LGJ2
TNFR-Cys domain-containing protein.
  
 0.741
A0A2C9KFC3
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
    
 0.732
A0A2C9K465
DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.
    
 0.710
Your Current Organism:
Biomphalaria glabrata
NCBI taxonomy Id: 6526
Other names: Australorbis glabratus, B. glabrata, Planorbis glabratus, bloodfluke planorb
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.