STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sucDsuccinyl-CoA synthetase alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (291 aa)    
Predicted Functional Partners:
sucC
succinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 0.999
SDS05773.1
Succinate dehydrogenase / fumarate reductase iron-sulfur subunit.
  
 0.991
SDS05813.1
Succinate dehydrogenase subunit A.
  
 0.987
SDS96039.1
2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase).
  
 0.980
SDT48559.1
2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 
 0.979
SDT54215.1
Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase).
  
 0.975
SDT48543.1
2-oxoglutarate dehydrogenase E1 component.
 
 
 0.954
SDT20611.1
Glutamate synthase (NADH) large subunit.
  
 
 0.937
mdh
Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
 
 0.930
SDT28760.1
Citrate synthase; Belongs to the citrate synthase family.
 
 0.922
Your Current Organism:
Mucilaginibacter mallensis
NCBI taxonomy Id: 652787
Other names: LMG 25360, LMG:25360, M. mallensis, Mucilaginibacter mallensis Mannisto et al. 2010, Mucilaginibacter sp. MP1X4, strain MP1X4
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