node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EHM94933.1 | EHM95029.1 | HMPREF0975_01046 | HMPREF0975_00897 | Hypothetical protein. | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.943 |
EHM94933.1 | EHM95256.1 | HMPREF0975_01046 | HMPREF0975_00689 | Hypothetical protein. | Hypothetical protein. | 0.911 |
EHM94933.1 | apt | HMPREF0975_01046 | HMPREF0975_01043 | Hypothetical protein. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.535 |
EHM94933.1 | ffh | HMPREF0975_01046 | HMPREF0975_00175 | Hypothetical protein. | Hypothetical protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.936 |
EHM94933.1 | ftsY | HMPREF0975_01046 | HMPREF0975_00180 | Hypothetical protein. | Hypothetical protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.936 |
EHM94933.1 | pheT | HMPREF0975_01046 | HMPREF0975_00015 | Hypothetical protein. | phenylalanyl-tRNA synthetase, beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.457 |
EHM94933.1 | secD | HMPREF0975_01046 | HMPREF0975_01045 | Hypothetical protein. | Preprotein translocase, SecD subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.917 |
EHM94933.1 | secE | HMPREF0975_01046 | HMPREF0975_01236 | Hypothetical protein. | Hypothetical protein; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.956 |
EHM94933.1 | secF | HMPREF0975_01046 | HMPREF0975_01044 | Hypothetical protein. | Hypothetical protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.872 |
EHM94933.1 | secY | HMPREF0975_01046 | HMPREF0975_01273 | Hypothetical protein. | Preprotein translocase subunit secY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.945 |
EHM95029.1 | EHM94933.1 | HMPREF0975_00897 | HMPREF0975_01046 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Hypothetical protein. | 0.943 |
EHM95029.1 | EHM95256.1 | HMPREF0975_00897 | HMPREF0975_00689 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Hypothetical protein. | 0.985 |
EHM95029.1 | ffh | HMPREF0975_00897 | HMPREF0975_00175 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Hypothetical protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.972 |
EHM95029.1 | ftsY | HMPREF0975_00897 | HMPREF0975_00180 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Hypothetical protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.993 |
EHM95029.1 | pheT | HMPREF0975_00897 | HMPREF0975_00015 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | phenylalanyl-tRNA synthetase, beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.487 |
EHM95029.1 | secD | HMPREF0975_00897 | HMPREF0975_01045 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Preprotein translocase, SecD subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.997 |
EHM95029.1 | secE | HMPREF0975_00897 | HMPREF0975_01236 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Hypothetical protein; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.999 |
EHM95029.1 | secF | HMPREF0975_00897 | HMPREF0975_01044 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Hypothetical protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.927 |
EHM95029.1 | secY | HMPREF0975_00897 | HMPREF0975_01273 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Preprotein translocase subunit secY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.999 |
EHM95256.1 | EHM94933.1 | HMPREF0975_00689 | HMPREF0975_01046 | Hypothetical protein. | Hypothetical protein. | 0.911 |