STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EHM94843.12-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase. (321 aa)    
Predicted Functional Partners:
EHM94963.1
Dihydrolipoyl dehydrogenase.
 0.999
EHM95506.1
Hypothetical protein.
 
0.996
EHM93566.1
Hypothetical protein.
 0.993
EHM94776.1
Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.990
EHM94964.1
Hypothetical protein.
  
  0.989
sucC
succinyl-CoA ligase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 
 0.984
sucD
Hypothetical protein; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 
 0.982
EHM92576.1
Citrate (Si)-synthase; Belongs to the citrate synthase family.
  
 0.960
EHM95101.1
Hypothetical protein.
  
 
 0.957
EHM94966.1
Hypothetical protein.
  
 
 0.957
Your Current Organism:
Actinomyces sp. F0330
NCBI taxonomy Id: 653386
Other names: A. sp. oral taxon 849 str. F0330, Actinomyces sp. oral taxon 849 str. F0330
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.