Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EHM91503.1Hypothetical protein. (508 aa)    
Predicted Functional Partners:
EHM95787.1
Phosphatidate cytidylyltransferase; Belongs to the CDS family.
     
 0.860
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 0.799
EHM92570.1
Hypothetical protein.
  
 
  0.631
trpB
Hypothetical protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine; Belongs to the TrpC family.
    
 0.592
EHM94068.1
CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
 
  
 0.592
EHM90267.1
Hypothetical protein.
    
 0.590
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.555
trpA
Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
    
 0.551
EHM95680.1
Cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family.
    
  0.532
EHM94590.1
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
    
  0.523
Your Current Organism:
Actinomyces sp. F0330
NCBI taxonomy Id: 653386
Other names: A. sp. oral taxon 849 str. F0330, Actinomyces sp. oral taxon 849 str. F0330
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