STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EHM90270.1Hypothetical protein. (797 aa)    
Predicted Functional Partners:
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.915
EHM94714.1
Adenosine deaminase.
    
 0.906
EHM94402.1
Hypothetical protein.
  
 
 0.899
EHM94291.1
Purine nucleoside phosphorylase.
     
  0.858
EHM95822.1
Hypothetical protein.
    
 0.840
EHM91240.1
Hypothetical protein.
  
 
 0.833
tdk
Thymidine kinase.
 
  
  0.832
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
    
 0.828
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.818
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
    
 0.816
Your Current Organism:
Actinomyces sp. F0330
NCBI taxonomy Id: 653386
Other names: A. sp. oral taxon 849 str. F0330, Actinomyces sp. oral taxon 849 str. F0330
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.