STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPOG_00999HAL protein kinase Hal4. (660 aa)    
Predicted Functional Partners:
SPOG_04179
ATR checkpoint kinase Rad3; Belongs to the PI3/PI4-kinase family.
    
 0.814
SPOG_03259
DNA helicase; Belongs to the MCM family.
   
 0.803
SPOG_01078
DNA replication pre-initiation complex subunit Cdc45.
   
 0.800
SPOG_03320
CAMK/RAD53 protein kinase Cds1; Belongs to the protein kinase superfamily.
  
0.782
SPOG_01544
M phase inducer phosphatase Cdc25.
   
 0.745
SPOG_01310
Cdc25 family phosphatase Ibp1.
   
 0.745
SPOG_00063
Exonuclease I Exo1.
   
 0.741
SPOG_01677
Guanyl-nucleotide exchange factor.
   
  
 0.726
SPOG_00054
Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
   
 0.710
SPOG_01456
WEE protein kinase Mik1.
  
0.697
Your Current Organism:
Schizosaccharomyces cryophilus
NCBI taxonomy Id: 653667
Other names: S. cryophilus OY26, Schizosaccharomyces cryophilus CBS 11777, Schizosaccharomyces cryophilus NBRC 106824, Schizosaccharomyces cryophilus NRRL Y-48691, Schizosaccharomyces cryophilus OY26, Schizosaccharomyces sp. OY26
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.