STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPOG_02963Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (921 aa)    
Predicted Functional Partners:
SPOG_00255
Citrate synthase; Belongs to the citrate synthase family.
  
 0.940
SPOG_04828
Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
  
 0.916
SPOG_01275
Isocitrate dehydrogenase [NAD] subunit, mitochondrial.
  
 0.904
SPOG_03861
Aconitate hydratase.
  
 
0.868
SPOG_02661
Isocitrate dehydrogenase [NAD] subunit, mitochondrial.
  
 0.833
SPOG_03008
Homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
 
 0.814
SPOG_02844
Ribosomal protein subunit Yml6.
   
 
 0.810
SPOG_01579
Homoaconitase, mitochondrial; Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis.
   
 
 
0.803
SPOG_00068
Uncharacterized protein.
    
 
 0.787
SPOG_02077
Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 0.741
Your Current Organism:
Schizosaccharomyces cryophilus
NCBI taxonomy Id: 653667
Other names: S. cryophilus OY26, Schizosaccharomyces cryophilus CBS 11777, Schizosaccharomyces cryophilus NBRC 106824, Schizosaccharomyces cryophilus NRRL Y-48691, Schizosaccharomyces cryophilus OY26, Schizosaccharomyces sp. OY26
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.