STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU66276.1KEGG: aar:Acear_1034 signal transduction histidine kinase, LytS; PFAM: histidine kinase internal region; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein. (582 aa)    
Predicted Functional Partners:
ADU66510.1
Response regulator receiver; KEGG: aar:Acear_1035 two component transcriptional regulator, LytTR family; PFAM: response regulator receiver; LytTr DNA-binding region; SMART: response regulator receiver.
 0.994
ADU66277.1
Glutathione transferase; KEGG: sme:SMc02708 hypothetical protein; PFAM: Glutathione S-transferase domain.
       0.727
ADU66278.1
KEGG: drt:Dret_0827 hypothetical protein.
       0.707
ADU64822.1
ATP-binding region ATPase domain protein; KEGG: syf:Synpcc7942_1816 periplasmic sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; Cache type 2 domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; response regulator receiver.
 
 
  
 0.706
ADU66517.1
KEGG: mhu:Mhun_2640 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein.
 
    
 0.603
nfo
Apurinic endonuclease Apn1; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.
       0.568
fumC
Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
       0.565
ADU66275.1
KEGG: glo:Glov_0569 response regulator receiver protein; PFAM: response regulator receiver; SMART: response regulator receiver.
     
 0.474
radA
DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
       0.418
ADU65787.1
TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; extracellular solute-binding protein family 3; PAS fold-3 domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein; KEGG: glo:Glov_2634 diguanylate cyclase with PAS/PAC sensor; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; extracellular solute-binding protein family 3; PAS domain containing protein; Hpt domain protein.
 
 
  
 0.414
Your Current Organism:
Desulfurispirillum indicum
NCBI taxonomy Id: 653733
Other names: D. indicum S5, Desulfurispirillum indicum S5, Desulfurispirillum indicum str. S5, Desulfurispirillum indicum strain S5, bacterium S5, dissimilatory selenate-respiring bacterium S5
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