STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
derSmall GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. (452 aa)    
Predicted Functional Partners:
gpsA
PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: syp:SYNPCC7002_A2853 NAD+ dependent glycerol-3-phosphate dehydrogenase; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
 
  
 0.894
panC/cmk
Pantoate/beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the N-terminal section; belongs to the pantothenate synthetase family.
  
 0.881
ACK72683.1
Pseudouridine synthase; PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: mar:MAE_37390 probable ribosomal large subunit pseudouridine synthase B; Belongs to the pseudouridine synthase RsuA family.
 
  
 0.820
ffh
Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.
 
  
 0.762
ftsY
Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
 
   
 0.750
ACK71826.1
PFAM: phosphatidate cytidylyltransferase; KEGG: mar:MAE_55360 phosphatidate cytidylyltransferase; Belongs to the CDS family.
  
     0.696
rplA
Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
  
  
 0.681
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
 
  
 0.650
ACK69340.1
PFAM: cobalt transport protein; KEGG: mar:MAE_00820 cobalt transport system permease protein CbiQ homolog.
  
  
 0.647
ACK70622.1
PFAM: pseudouridine synthase; KEGG: mar:MAE_17490 ribosomal large subunit pseudouridine synthase E; Belongs to the pseudouridine synthase RsuA family.
 
  
 0.647
Your Current Organism:
Gloeothece citriformis
NCBI taxonomy Id: 65393
Other names: Cyanothece sp. PCC 7424, G. citriformis PCC 7424, Gloeothece citriformis PCC 7424, Synechococcus sp. ATCC 29155 (no longer available), Synechococcus sp. PCC 7424
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