STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (172 aa)    
Predicted Functional Partners:
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
 0.993
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
 
 0.967
ACK72124.1
TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: syn:sll0421 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
 0.964
purH
Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; KEGG: mar:MAE_62320 bifunctional phosphoribosyl aminoimidazole carboxy formyl formyltransferase/inosinemonophosphate cyclohydrolase; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: MGS domain protein; AICARFT/IMPCHase bienzyme formylation region.
  
 0.959
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
  
 
 0.943
ACK70998.1
PFAM: glutamine amidotransferase class-I; KEGG: aeh:Mlg_1637 glutamine amidotransferase class-I.
  
 
 0.941
ACK71981.1
PFAM: 5'-Nucleotidase domain protein; KEGG: syf:Synpcc7942_1392 alkaline phosphatase.
    
 0.924
ACK70349.1
TIGRFAM: stationary-phase survival protein SurE; PFAM: Survival protein SurE; KEGG: npu:Npun_R1763 stationary-phase survival protein SurE.
    
 0.911
surE
Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
 0.911
ACK73423.1
PFAM: CMP/dCMP deaminase zinc-binding; KEGG: bba:Bd0085 cytidine/deoxycytidylate deaminase family protein.
  
 
  0.905
Your Current Organism:
Gloeothece citriformis
NCBI taxonomy Id: 65393
Other names: Cyanothece sp. PCC 7424, G. citriformis PCC 7424, Gloeothece citriformis PCC 7424, Synechococcus sp. ATCC 29155 (no longer available), Synechococcus sp. PCC 7424
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