STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sasAHistidine kinase; May be involved in signal transduction. Participates in the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria, via its interaction with KaiC. Required for robustness of the circadian rhythm of gene expression and is involved in clock outputs. (393 aa)    
Predicted Functional Partners:
ACK72021.1
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: mar:MAE_14910 two-component response regulator OmpR subfamily.
 
  0.976
ACK73079.1
PFAM: Osmosensitive K channel His kinase sensor; UspA domain protein; KEGG: ana:all4242 potassium-dependent ATPase subunit D'.
 
      0.900
kaiC
Putative circadian clock protein, KaiC; Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction; Belongs to the KaiC family.
    
 
 0.825
ACK71408.1
KEGG: mar:MAE_39130 circadian clock protein KaiC homolog; TIGRFAM: circadian clock protein KaiC; PFAM: Circadian clock protein KaiC central region; KaiA binding.
    
 
 0.825
ACK71402.1
PFAM: response regulator receiver; KEGG: syn:slr1042 two-component response regulator (CheY subfamily), required for motility and transformation competency.
 
   0.818
ACK72342.1
PFAM: response regulator receiver; KEGG: tel:tll2438 two-component response regulator.
 
   0.803
ACK71204.1
PFAM: response regulator receiver; KEGG: syf:Synpcc7942_0856 response regulator receiver domain-containing protein.
  
   0.799
ACK70689.1
Two component transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein AraC type; response regulator receiver; KEGG: npu:Npun_F4909 two component AraC family transcriptional regulator.
 
 0.794
ACK71198.1
PFAM: response regulator receiver; KEGG: syn:sll0039 two-component response regulator (CheY subfamily).
  
   0.788
ACK72967.1
PFAM: response regulator receiver; KEGG: amr:AM1_3742 response regulator.
  
   0.785
Your Current Organism:
Gloeothece citriformis
NCBI taxonomy Id: 65393
Other names: Cyanothece sp. PCC 7424, G. citriformis PCC 7424, Gloeothece citriformis PCC 7424, Synechococcus sp. ATCC 29155 (no longer available), Synechococcus sp. PCC 7424
Server load: low (26%) [HD]