node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SER37143.1 | SER44161.1 | SAMN05216589_0348 | SAMN05216589_0568 | Biotin-requiring enzyme. | NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.900 |
SER37143.1 | SER44543.1 | SAMN05216589_0348 | SAMN05216589_0578 | Biotin-requiring enzyme. | Phosphotransacetylase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.829 |
SER37143.1 | SES05344.1 | SAMN05216589_0348 | SAMN05216589_2188 | Biotin-requiring enzyme. | Indolepyruvate ferredoxin oxidoreductase. | 0.839 |
SER37143.1 | SES09280.1 | SAMN05216589_0348 | SAMN05216589_2243 | Biotin-requiring enzyme. | Short chain enoyl-CoA hydratase; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family. | 0.915 |
SER37143.1 | SES10507.1 | SAMN05216589_0348 | SAMN05216589_2305 | Biotin-requiring enzyme. | 2-methylcitrate synthase; Belongs to the citrate synthase family. | 0.904 |
SER37143.1 | SES13977.1 | SAMN05216589_0348 | SAMN05216589_2456 | Biotin-requiring enzyme. | Citrate synthase; Belongs to the citrate synthase family. | 0.904 |
SER37143.1 | SES16503.1 | SAMN05216589_0348 | SAMN05216589_2473 | Biotin-requiring enzyme. | succinyl-CoA:acetate CoA-transferase. | 0.826 |
SER37143.1 | SES37506.1 | SAMN05216589_0348 | SAMN05216589_0083 | Biotin-requiring enzyme. | 3-hydroxyacyl-CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.915 |
SER37143.1 | sucC | SAMN05216589_0348 | SAMN05216589_2447 | Biotin-requiring enzyme. | succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.828 |
SER37143.1 | sucD | SAMN05216589_0348 | SAMN05216589_2446 | Biotin-requiring enzyme. | succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.822 |
SER44161.1 | SER37143.1 | SAMN05216589_0568 | SAMN05216589_0348 | NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Biotin-requiring enzyme. | 0.900 |
SER44161.1 | SER44543.1 | SAMN05216589_0568 | SAMN05216589_0578 | NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Phosphotransacetylase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.824 |
SER44161.1 | SES05344.1 | SAMN05216589_0568 | SAMN05216589_2188 | NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Indolepyruvate ferredoxin oxidoreductase. | 0.696 |
SER44161.1 | SES09280.1 | SAMN05216589_0568 | SAMN05216589_2243 | NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Short chain enoyl-CoA hydratase; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family. | 0.935 |
SER44161.1 | SES10507.1 | SAMN05216589_0568 | SAMN05216589_2305 | NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 2-methylcitrate synthase; Belongs to the citrate synthase family. | 0.744 |
SER44161.1 | SES13977.1 | SAMN05216589_0568 | SAMN05216589_2456 | NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Citrate synthase; Belongs to the citrate synthase family. | 0.744 |
SER44161.1 | SES16503.1 | SAMN05216589_0568 | SAMN05216589_2473 | NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | succinyl-CoA:acetate CoA-transferase. | 0.742 |
SER44161.1 | SES37506.1 | SAMN05216589_0568 | SAMN05216589_0083 | NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 3-hydroxyacyl-CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.935 |
SER44161.1 | sucC | SAMN05216589_0568 | SAMN05216589_2447 | NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.519 |
SER44161.1 | sucD | SAMN05216589_0568 | SAMN05216589_2446 | NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.539 |