STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SER39193.1ATPase family associated with various cellular activities (AAA). (1474 aa)    
Predicted Functional Partners:
SER39169.1
Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain.
 
   
 0.968
SER39143.1
Hypothetical protein.
 
     0.961
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.958
SER97342.1
DNA helicase-2 / ATP-dependent DNA helicase PcrA.
  
 0.956
SEP88016.1
Calcineurin-like phosphoesterase.
 
 0.950
sbcD
Exodeoxyribonuclease I subunit D; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
  
 0.944
SES22226.1
Calcineurin-like phosphoesterase.
  
 0.944
SES40020.1
DNA repair exonuclease SbcCD nuclease subunit.
  
 0.944
SEQ32735.1
5'-3' exonuclease.
  
 0.913
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
 0.894
Your Current Organism:
Lentzea albida
NCBI taxonomy Id: 65499
Other names: Asiosporangium albidum, DSM 44437, IFO 16102, JCM 10670, L. albida, Lentzea albida Labeda et al. 2001, NBRC 16102, NRRL B-24073, Saccharothrix aerocolonigenes subsp. staurosporea, Streptomyces stauroporeus, Streptomyces staurosporeus
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