STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurrence
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[Homology]
Score
ubiA4-hydroxybenzoate polyprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. (280 aa)    
Predicted Functional Partners:
atpD
F0F1-type ATP synthase, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.
    
  0.904
EEZ79835.1
FAD/FMN-containing dehydrogenase.
    
 0.902
EEZ79525.1
Glycolate oxidase subunit GlcD.
    
 0.889
EEZ80310.1
Glycolate oxidase subunit glcE.
    
 0.889
EEZ80129.1
2-polyprenyl-6-methoxyphenol hydroxylase.
  
  
 0.861
ubiE
Ubiquinone/menaquinone biosynthesis methyltransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2).
 
  
 0.850
EEZ80379.1
3-polyprenyl-4-hydroxybenzoate decarboxylase; Belongs to the UbiD family.
 
  
 0.836
ubiX
3-polyprenyl-4-hydroxybenzoate decarboxylase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family.
 
  
 0.826
EEZ80424.1
Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.
 
 
 0.821
EEZ79586.1
2-polyprenyl-6-methoxyphenol hydroxylase.
  
  
 0.786
Your Current Organism:
uncultured SUP05 cluster
NCBI taxonomy Id: 655186
Other names: u. SUP05 cluster bacterium, uncultured SUP05 cluster bacterium
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