STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tsaDMetal-dependent protease; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (340 aa)    
Predicted Functional Partners:
EEZ80543.1
Glycoprotease.
  
 0.999
EEZ80138.1
ABC-type transport system, ATPase component.
 
     0.824
EEZ79637.1
Translation factor SUA5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.
  
 
 0.794
EEZ80136.1
Mg(2+) chelatase family protein.
       0.773
EEZ79611.1
Histone acetyltransferase HPA2.
  
 
 0.757
EEZ79648.1
N-acetylglutamate synthase; Belongs to the acetyltransferase family.
    
  0.741
EEZ80156.1
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
    
  0.729
hisA
Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide isomerase.
  
    0.719
EEZ80135.1
Mg chelatase-related protein.
       0.709
EEZ80133.1
Hypothetical protein; Belongs to the UPF0125 (RnfH) family.
       0.681
Your Current Organism:
uncultured SUP05 cluster
NCBI taxonomy Id: 655186
Other names: u. SUP05 cluster bacterium, uncultured SUP05 cluster bacterium
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.