STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EEZ80781.1Thiamine monophosphate synthase; Belongs to the Nudix hydrolase family. (307 aa)    
Predicted Functional Partners:
EEZ80093.1
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase.
 
 
 0.975
thiG
Hypothetical protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
 
 0.964
EEZ80378.1
Thiamine biosynthesis protein ThiC.
  
 
 0.915
ribB
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
    
 0.792
thiE
Thiamine monophosphate synthase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
  
  
  0.789
guaA
GMP synthase, PP-ATPase domain/subunit; Catalyzes the synthesis of GMP from XMP.
    
 0.722
EEZ79890.1
Fumarate hydratase, class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
    
  0.716
EEZ80452.1
Hypothetical protein.
 
  
  0.706
EEZ80297.1
Thiamine monophosphate synthase; Belongs to the Nudix hydrolase family.
 
  
0.690
EEZ80497.1
ADP-ribose diphosphatase NudE.
  
 
 0.686
Your Current Organism:
uncultured SUP05 cluster
NCBI taxonomy Id: 655186
Other names: u. SUP05 cluster bacterium, uncultured SUP05 cluster bacterium
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.