SFO84633.1 protein (Cohaesibacter marisflavi)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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[Homology]

Score

SFO84633.1

Type VI secretion system protein ImpG. (624 aa)

Predicted Functional Partners:

SFO84589.1

0.993

SFO84733.1

0.990

SFO84528.1

0.987

SFO84934.1

0.987

SFO84908.1

0.986

SFO84611.1

0.984

SFO84657.1

0.983

SFO84501.1

0.973

SFO84545.1

0.966

SFO84684.1

0.952

Your Current Organism:

Cohaesibacter marisflavi

NCBI taxonomy Id: 655353
Other names: C. marisflavi, CGMCC 1.9157, Cohaesibacter marisflavi Qu et al. 2011, Cohaesibacter sp. DQHS21, NCCB 100300, strain DQHS21

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SFO84501.1	SFO84528.1	SAMN04488056_11413	SAMN04488056_11414	Type VI secretion system protein ImpB.	Type VI secretion system protein ImpC.	0.999
SFO84501.1	SFO84545.1	SAMN04488056_11413	SAMN04488056_11415	Type VI secretion system protein ImpB.	Type VI secretion system secreted protein Hcp.	0.999
SFO84501.1	SFO84589.1	SAMN04488056_11413	SAMN04488056_11416	Type VI secretion system protein ImpB.	Type VI secretion system protein ImpE.	0.997
SFO84501.1	SFO84611.1	SAMN04488056_11413	SAMN04488056_11417	Type VI secretion system protein ImpB.	Type VI secretion system protein ImpF.	0.981
SFO84501.1	SFO84633.1	SAMN04488056_11413	SAMN04488056_11418	Type VI secretion system protein ImpB.	Type VI secretion system protein ImpG.	0.973
SFO84501.1	SFO84657.1	SAMN04488056_11413	SAMN04488056_11419	Type VI secretion system protein ImpB.	Type VI secretion system protein ImpH.	0.989
SFO84501.1	SFO84684.1	SAMN04488056_11413	SAMN04488056_11420	Type VI secretion system protein ImpB.	Type VI secretion system protein VasG; Belongs to the ClpA/ClpB family.	0.962
SFO84501.1	SFO84733.1	SAMN04488056_11413	SAMN04488056_11422	Type VI secretion system protein ImpB.	Type VI secretion protein, EvpB/VC_A0108 family/type VI secretion protein, VC_A0107 family.	0.990
SFO84501.1	SFO84908.1	SAMN04488056_11413	SAMN04488056_11429	Type VI secretion system protein ImpB.	Type VI secretion system protein ImpJ.	0.992
SFO84501.1	SFO84934.1	SAMN04488056_11413	SAMN04488056_11430	Type VI secretion system protein ImpB.	Type VI secretion system protein ImpK.	0.985
SFO84528.1	SFO84501.1	SAMN04488056_11414	SAMN04488056_11413	Type VI secretion system protein ImpC.	Type VI secretion system protein ImpB.	0.999
SFO84528.1	SFO84545.1	SAMN04488056_11414	SAMN04488056_11415	Type VI secretion system protein ImpC.	Type VI secretion system secreted protein Hcp.	0.998
SFO84528.1	SFO84589.1	SAMN04488056_11414	SAMN04488056_11416	Type VI secretion system protein ImpC.	Type VI secretion system protein ImpE.	0.982
SFO84528.1	SFO84611.1	SAMN04488056_11414	SAMN04488056_11417	Type VI secretion system protein ImpC.	Type VI secretion system protein ImpF.	0.971
SFO84528.1	SFO84633.1	SAMN04488056_11414	SAMN04488056_11418	Type VI secretion system protein ImpC.	Type VI secretion system protein ImpG.	0.987
SFO84528.1	SFO84657.1	SAMN04488056_11414	SAMN04488056_11419	Type VI secretion system protein ImpC.	Type VI secretion system protein ImpH.	0.984
SFO84528.1	SFO84684.1	SAMN04488056_11414	SAMN04488056_11420	Type VI secretion system protein ImpC.	Type VI secretion system protein VasG; Belongs to the ClpA/ClpB family.	0.990
SFO84528.1	SFO84733.1	SAMN04488056_11414	SAMN04488056_11422	Type VI secretion system protein ImpC.	Type VI secretion protein, EvpB/VC_A0108 family/type VI secretion protein, VC_A0107 family.	0.993
SFO84528.1	SFO84908.1	SAMN04488056_11414	SAMN04488056_11429	Type VI secretion system protein ImpC.	Type VI secretion system protein ImpJ.	0.976
SFO84528.1	SFO84934.1	SAMN04488056_11414	SAMN04488056_11430	Type VI secretion system protein ImpC.	Type VI secretion system protein ImpK.	0.986

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Network Stats

number of nodes:

11

number of edges:

34

average node degree:

6.18

avg. local clustering coefficient:

0.859

expected number of edges:

46

PPI enrichment p-value:

0.973

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006537

Glutamate biosynthetic process

6 of 6

2.55

5.07

1.21e-10

GO:0009084

Glutamine family amino acid biosynthetic process

7 of 30

1.92

3.81

4.25e-10

GO:0009064

Glutamine family amino acid metabolic process

8 of 53

1.73

3.37

2.48e-10

GO:0006541

Glutamine metabolic process

4 of 25

1.75

1.87

6.80e-05

GO:0006520

Cellular amino acid metabolic process

9 of 219

1.16

1.52

7.93e-08

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016639

Oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor

6 of 8

2.42

4.82

2.18e-10

GO:0004355

Glutamate synthase (NADPH) activity

5 of 5

2.55

4.31

4.84e-09

GO:0016491

Oxidoreductase activity

7 of 516

0.68

0.44

0.0196

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:756

Oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor, and GXGXG motif

8 of 10

2.45

6.85

4.96e-15

CL:759

GXGXG motif, and Oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor

5 of 5

2.55

4.49

2.00e-09

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00680

Methane metabolism

4 of 40

1.55

1.39

0.00059

map00910

Nitrogen metabolism

3 of 25

1.63

1.17

0.0032

map00250

Alanine, aspartate and glutamate metabolism

3 of 35

1.48

1.04

0.0045

map01120

Microbial metabolism in diverse environments

7 of 432

0.76

0.57

0.0032

map01100

Metabolic pathways

10 of 1571

0.35

0.27

0.0222

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0031026

Glutamate synthase complex

2 of 2

2.55

1.03

0.0130

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF01645

Conserved region in glutamate synthase

3 of 3

2.55

2.01

0.00019

PF01493

GXGXG motif

2 of 2

2.55

1.04

0.0127

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