node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SFF38993.1 | SFF46999.1 | SAMN05216283_105206 | SAMN05216283_10747 | Cytidylate kinase. | IMP dehydrogenase. | 0.670 |
SFF38993.1 | guaB | SAMN05216283_105206 | SAMN05216283_103240 | Cytidylate kinase. | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.670 |
SFF38993.1 | rplB | SAMN05216283_105206 | SAMN05216283_102483 | Cytidylate kinase. | Large subunit ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. | 0.671 |
SFF38993.1 | rplC | SAMN05216283_105206 | SAMN05216283_102480 | Cytidylate kinase. | Large subunit ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 0.664 |
SFF38993.1 | rplE | SAMN05216283_105206 | SAMN05216283_102492 | Cytidylate kinase. | Large subunit ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. | 0.676 |
SFF38993.1 | rplN | SAMN05216283_105206 | SAMN05216283_102490 | Cytidylate kinase. | Large subunit ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. | 0.679 |
SFF38993.1 | rplV | SAMN05216283_105206 | SAMN05216283_102485 | Cytidylate kinase. | Large subunit ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. | 0.679 |
SFF38993.1 | rplW | SAMN05216283_105206 | SAMN05216283_102482 | Cytidylate kinase. | Large subunit ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. | 0.669 |
SFF38993.1 | rplX | SAMN05216283_105206 | SAMN05216283_102491 | Cytidylate kinase. | Large subunit ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit. | 0.679 |
SFF38993.1 | rpmC | SAMN05216283_105206 | SAMN05216283_102488 | Cytidylate kinase. | Large subunit ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family. | 0.665 |
SFF46999.1 | SFF38993.1 | SAMN05216283_10747 | SAMN05216283_105206 | IMP dehydrogenase. | Cytidylate kinase. | 0.670 |
SFF46999.1 | guaB | SAMN05216283_10747 | SAMN05216283_103240 | IMP dehydrogenase. | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.813 |
SFF46999.1 | rplC | SAMN05216283_10747 | SAMN05216283_102480 | IMP dehydrogenase. | Large subunit ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 0.435 |
SFF46999.1 | rplE | SAMN05216283_10747 | SAMN05216283_102492 | IMP dehydrogenase. | Large subunit ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. | 0.408 |
SFF46999.1 | rpmC | SAMN05216283_10747 | SAMN05216283_102488 | IMP dehydrogenase. | Large subunit ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family. | 0.415 |
guaB | SFF38993.1 | SAMN05216283_103240 | SAMN05216283_105206 | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Cytidylate kinase. | 0.670 |
guaB | SFF46999.1 | SAMN05216283_103240 | SAMN05216283_10747 | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | IMP dehydrogenase. | 0.813 |
guaB | rplC | SAMN05216283_103240 | SAMN05216283_102480 | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Large subunit ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 0.435 |
guaB | rplE | SAMN05216283_103240 | SAMN05216283_102492 | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Large subunit ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. | 0.408 |
guaB | rpmC | SAMN05216283_103240 | SAMN05216283_102488 | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Large subunit ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family. | 0.415 |