Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ZPR_0488uroporphyrinogen-III synthase. (248 aa)    
Predicted Functional Partners:
ZPR_0112
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.973
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
  
 
 0.921
ZPR_3630
uroporphyrin-III C-methyltransferase.
  
 
 0.921
ZPR_0111
uroporphyrinogen-III synthase.
     
  0.900
ZPR_2529
Conserved hypothetical protein.
  
     0.772
ZPR_3095
Conserved hypothetical protein.
  
     0.768
ZPR_0489
Membrane protein.
       0.757
ZPR_0415
Conserved hypothetical protein.
 
     0.752
ZPR_0799
Conserved hypothetical protein.
  
     0.746
ZPR_4624
Conserved hypothetical protein.
  
     0.739
Your Current Organism:
Zunongwangia profunda
NCBI taxonomy Id: 655815
Other names: Z. profunda SM-A87, Zunongwangia profunda SM-A87, Zunongwangia profunda str. SM-A87, Zunongwangia profunda strain SM-A87
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