Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ZPR_0631Pyruvate dehydrogenase subunit E1; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (887 aa)    
Predicted Functional Partners:
ZPR_0632
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex.
 
 0.998
ZPR_0633
E3 component of pyruvate dehydrogenase complex.
 
 0.991
ZPR_3923
Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 0.978
ZPR_2851
Dihydrolipoamide dehydrogenase.
 
 0.960
ZPR_4064
Dihydrolipoamide dehydrogenase, E3 component of 2-oxoglutarate and pyruvate dehydrogenase complexes.
 
 0.959
ZPR_1874
Dihydrolipoamide dehydrogenase.
  
 0.954
ZPR_0588
Malic enzyme.
  
 
 0.949
ZPR_0282
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.928
pdhA
Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
    
 0.909
ZPR_1552
L-lactate dehydrogenase.
     
 0.908
Your Current Organism:
Zunongwangia profunda
NCBI taxonomy Id: 655815
Other names: Z. profunda SM-A87, Zunongwangia profunda SM-A87, Zunongwangia profunda str. SM-A87, Zunongwangia profunda strain SM-A87
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.