STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZPR_1657Thiamine pyrophosphate protein domain protein TPP-binding; Belongs to the TPP enzyme family. (579 aa)    
Predicted Functional Partners:
ZPR_2801
Acetolactate synthase small subunit.
 0.991
ZPR_0588
Malic enzyme.
  
 
 0.949
ZPR_1552
L-lactate dehydrogenase.
  
 
 0.928
leuD
3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
 
 
 0.928
ZPR_2958
L-lactate dehydrogenase and related alpha-hydroxy acid dehydrogenase.
  
 
 0.928
ZPR_0282
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.924
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
    
 0.918
ZPR_1838
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
   
 
 0.915
ZPR_0298
Aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family.
 
 0.914
ZPR_3649
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
 
 0.914
Your Current Organism:
Zunongwangia profunda
NCBI taxonomy Id: 655815
Other names: Z. profunda SM-A87, Zunongwangia profunda SM-A87, Zunongwangia profunda str. SM-A87, Zunongwangia profunda strain SM-A87
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