| node1 | node2 | node1 annotation | node2 annotation | score |
| ZPR_1469 | ZPR_1838 | methylmalonyl-CoA mutase. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.479 |
| ZPR_1469 | ZPR_1999 | methylmalonyl-CoA mutase. | acyl-CoA carboxylase carboxyl transferase beta subunit. | 0.738 |
| ZPR_1469 | ZPR_2469 | methylmalonyl-CoA mutase. | 3-hydroxyacyl-CoA dehydrogenase. | 0.545 |
| ZPR_1469 | ZPR_4689 | methylmalonyl-CoA mutase. | Lactoylglutathione lyase. | 0.980 |
| ZPR_1838 | ZPR_1469 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | methylmalonyl-CoA mutase. | 0.479 |
| ZPR_1838 | ZPR_1999 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | acyl-CoA carboxylase carboxyl transferase beta subunit. | 0.925 |
| ZPR_1838 | ZPR_2291 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 6-phosphogluconate dehydrogenase. | 0.834 |
| ZPR_1838 | ZPR_2468 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 3-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.878 |
| ZPR_1838 | ZPR_2469 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 3-hydroxyacyl-CoA dehydrogenase. | 0.581 |
| ZPR_1838 | ZPR_2538 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.937 |
| ZPR_1838 | ZPR_4620 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.920 |
| ZPR_1997 | ZPR_1998 | Biotin carboxyl carrier protein of acyl-CoA carboxylase. | Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.983 |
| ZPR_1997 | ZPR_1999 | Biotin carboxyl carrier protein of acyl-CoA carboxylase. | acyl-CoA carboxylase carboxyl transferase beta subunit. | 0.981 |
| ZPR_1997 | ZPR_2469 | Biotin carboxyl carrier protein of acyl-CoA carboxylase. | 3-hydroxyacyl-CoA dehydrogenase. | 0.479 |
| ZPR_1998 | ZPR_1997 | Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Biotin carboxyl carrier protein of acyl-CoA carboxylase. | 0.983 |
| ZPR_1998 | ZPR_1999 | Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | acyl-CoA carboxylase carboxyl transferase beta subunit. | 0.993 |
| ZPR_1998 | ZPR_2469 | Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 3-hydroxyacyl-CoA dehydrogenase. | 0.479 |
| ZPR_1999 | ZPR_1469 | acyl-CoA carboxylase carboxyl transferase beta subunit. | methylmalonyl-CoA mutase. | 0.738 |
| ZPR_1999 | ZPR_1838 | acyl-CoA carboxylase carboxyl transferase beta subunit. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.925 |
| ZPR_1999 | ZPR_1997 | acyl-CoA carboxylase carboxyl transferase beta subunit. | Biotin carboxyl carrier protein of acyl-CoA carboxylase. | 0.981 |