node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ZPR_0236 | ZPR_2009 | ZPR_0236 | ZPR_2009 | single-stranded-DNA-specific exonuclease RecJ. | ATP-dependent DNA helicase RecQ. | 0.910 |
ZPR_0236 | mutL | ZPR_0236 | ZPR_1458 | single-stranded-DNA-specific exonuclease RecJ. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.635 |
ZPR_0236 | polA | ZPR_0236 | ZPR_0517 | single-stranded-DNA-specific exonuclease RecJ. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.549 |
ZPR_0236 | topA | ZPR_0236 | ZPR_4152 | single-stranded-DNA-specific exonuclease RecJ. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.479 |
ZPR_1779 | ZPR_2009 | ZPR_1779 | ZPR_2009 | DNA double-strand break repair rad50 ATPase. | ATP-dependent DNA helicase RecQ. | 0.652 |
ZPR_1779 | polA | ZPR_1779 | ZPR_0517 | DNA double-strand break repair rad50 ATPase. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.874 |
ZPR_1779 | recA | ZPR_1779 | ZPR_0086 | DNA double-strand break repair rad50 ATPase. | RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.659 |
ZPR_1779 | sbcD | ZPR_1779 | ZPR_2877 | DNA double-strand break repair rad50 ATPase. | Exonuclease SbcD; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. | 0.954 |
ZPR_1779 | topA | ZPR_1779 | ZPR_4152 | DNA double-strand break repair rad50 ATPase. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.723 |
ZPR_1841 | ZPR_2009 | ZPR_1841 | ZPR_2009 | DNA topoisomerase I-like protein. | ATP-dependent DNA helicase RecQ. | 0.690 |
ZPR_1841 | polA | ZPR_1841 | ZPR_0517 | DNA topoisomerase I-like protein. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.440 |
ZPR_1841 | sbcD | ZPR_1841 | ZPR_2877 | DNA topoisomerase I-like protein. | Exonuclease SbcD; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. | 0.467 |
ZPR_1841 | topA | ZPR_1841 | ZPR_4152 | DNA topoisomerase I-like protein. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.425 |
ZPR_2009 | ZPR_0236 | ZPR_2009 | ZPR_0236 | ATP-dependent DNA helicase RecQ. | single-stranded-DNA-specific exonuclease RecJ. | 0.910 |
ZPR_2009 | ZPR_1779 | ZPR_2009 | ZPR_1779 | ATP-dependent DNA helicase RecQ. | DNA double-strand break repair rad50 ATPase. | 0.652 |
ZPR_2009 | ZPR_1841 | ZPR_2009 | ZPR_1841 | ATP-dependent DNA helicase RecQ. | DNA topoisomerase I-like protein. | 0.690 |
ZPR_2009 | ZPR_2878 | ZPR_2009 | ZPR_2878 | ATP-dependent DNA helicase RecQ. | ATP/GTP-binding site motif A (P-loop):ABC transporter. | 0.671 |
ZPR_2009 | gmk | ZPR_2009 | ZPR_0334 | ATP-dependent DNA helicase RecQ. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.715 |
ZPR_2009 | mutL | ZPR_2009 | ZPR_1458 | ATP-dependent DNA helicase RecQ. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.684 |
ZPR_2009 | polA | ZPR_2009 | ZPR_0517 | ATP-dependent DNA helicase RecQ. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.856 |