Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ZPR_2016Universal stress protein. (266 aa)    
Predicted Functional Partners:
ZPR_2015
Putative diguanylate phosphodiesterase (EAL domain) with Response Regulator Receiver modulation.
 
  
 0.862
ZPR_2014
Sensory transduction histidine kinase.
 
   
 0.798
gyrA
DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
     
 0.634
ZPR_1694
2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
   
  
 0.633
ZPR_0229
Asparagine synthetase B.
      
 0.618
ZPR_0875
Phytoene synthase.
      
 0.618
ZPR_1112
Asparagine synthetase.
      
 0.618
ZPR_0878
Conserved hypothetical protein.
  
     0.508
ZPR_2302
Conserved hypothetical protein.
  
    0.455
ZPR_2305
Conserved hypothetical protein.
 
    0.445
Your Current Organism:
Zunongwangia profunda
NCBI taxonomy Id: 655815
Other names: Z. profunda SM-A87, Zunongwangia profunda SM-A87, Zunongwangia profunda str. SM-A87, Zunongwangia profunda strain SM-A87
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