| node1 | node2 | node1 annotation | node2 annotation | score |
| ZPR_0624 | ZPR_2291 | Alpha/beta superfamily hydrolase. | 6-phosphogluconate dehydrogenase. | 0.503 |
| ZPR_0863 | ZPR_1999 | hydroxymethylglutaryl-CoA lyase-like protein. | acyl-CoA carboxylase carboxyl transferase beta subunit. | 0.514 |
| ZPR_0863 | ZPR_2291 | hydroxymethylglutaryl-CoA lyase-like protein. | 6-phosphogluconate dehydrogenase. | 0.442 |
| ZPR_0863 | ZPR_2469 | hydroxymethylglutaryl-CoA lyase-like protein. | 3-hydroxyacyl-CoA dehydrogenase. | 0.669 |
| ZPR_1296 | ZPR_2291 | Carboxymuconolactone decarboxylase. | 6-phosphogluconate dehydrogenase. | 0.400 |
| ZPR_1838 | ZPR_1999 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | acyl-CoA carboxylase carboxyl transferase beta subunit. | 0.925 |
| ZPR_1838 | ZPR_2291 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 6-phosphogluconate dehydrogenase. | 0.834 |
| ZPR_1838 | ZPR_2469 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 3-hydroxyacyl-CoA dehydrogenase. | 0.581 |
| ZPR_1838 | ZPR_2538 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.937 |
| ZPR_1999 | ZPR_0863 | acyl-CoA carboxylase carboxyl transferase beta subunit. | hydroxymethylglutaryl-CoA lyase-like protein. | 0.514 |
| ZPR_1999 | ZPR_1838 | acyl-CoA carboxylase carboxyl transferase beta subunit. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.925 |
| ZPR_1999 | ZPR_2291 | acyl-CoA carboxylase carboxyl transferase beta subunit. | 6-phosphogluconate dehydrogenase. | 0.810 |
| ZPR_1999 | ZPR_2469 | acyl-CoA carboxylase carboxyl transferase beta subunit. | 3-hydroxyacyl-CoA dehydrogenase. | 0.722 |
| ZPR_1999 | ZPR_2538 | acyl-CoA carboxylase carboxyl transferase beta subunit. | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.905 |
| ZPR_2290 | ZPR_2291 | CDF family cation efflux protein. | 6-phosphogluconate dehydrogenase. | 0.505 |
| ZPR_2290 | ZPR_2292 | CDF family cation efflux protein. | Formate/nitrite transporter. | 0.489 |
| ZPR_2291 | ZPR_0624 | 6-phosphogluconate dehydrogenase. | Alpha/beta superfamily hydrolase. | 0.503 |
| ZPR_2291 | ZPR_0863 | 6-phosphogluconate dehydrogenase. | hydroxymethylglutaryl-CoA lyase-like protein. | 0.442 |
| ZPR_2291 | ZPR_1296 | 6-phosphogluconate dehydrogenase. | Carboxymuconolactone decarboxylase. | 0.400 |
| ZPR_2291 | ZPR_1838 | 6-phosphogluconate dehydrogenase. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.834 |