| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ZPR_0856 | ZPR_3586 | ZPR_0856 | ZPR_3586 | Antitermination protein NusB. | Bifunctional riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.655 |
| ZPR_0856 | ribB | ZPR_0856 | ZPR_2864 | Antitermination protein NusB. | Bifunctional protein: GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.615 |
| ZPR_0856 | ribH | ZPR_0856 | ZPR_1456 | Antitermination protein NusB. | Riboflavin synthase subunit beta; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.772 |
| ZPR_0979 | ZPR_3586 | ZPR_0979 | ZPR_3586 | Dihydropteroate synthase. | Bifunctional riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.661 |
| ZPR_0979 | ZPR_3737 | ZPR_0979 | ZPR_3737 | Dihydropteroate synthase. | HPPK and dNK domain-containing protein. | 0.992 |
| ZPR_0979 | ZPR_4626 | ZPR_0979 | ZPR_4626 | Dihydropteroate synthase. | Riboflavin synthase subunit alpha. | 0.461 |
| ZPR_0979 | ribB | ZPR_0979 | ZPR_2864 | Dihydropteroate synthase. | Bifunctional protein: GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.599 |
| ZPR_0979 | ribH | ZPR_0979 | ZPR_1456 | Dihydropteroate synthase. | Riboflavin synthase subunit beta; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.719 |
| ZPR_3586 | ZPR_0856 | ZPR_3586 | ZPR_0856 | Bifunctional riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Antitermination protein NusB. | 0.655 |
| ZPR_3586 | ZPR_0979 | ZPR_3586 | ZPR_0979 | Bifunctional riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Dihydropteroate synthase. | 0.661 |
| ZPR_3586 | ZPR_3587 | ZPR_3586 | ZPR_3587 | Bifunctional riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Haloacid dehalogenase-like hydrolase. | 0.920 |
| ZPR_3586 | ZPR_3588 | ZPR_3586 | ZPR_3588 | Bifunctional riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Conserved hypothetical protein. | 0.736 |
| ZPR_3586 | ZPR_3737 | ZPR_3586 | ZPR_3737 | Bifunctional riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | HPPK and dNK domain-containing protein. | 0.707 |
| ZPR_3586 | ZPR_4626 | ZPR_3586 | ZPR_4626 | Bifunctional riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Riboflavin synthase subunit alpha. | 0.999 |
| ZPR_3586 | eno | ZPR_3586 | ZPR_3847 | Bifunctional riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.959 |
| ZPR_3586 | nadD | ZPR_3586 | ZPR_0333 | Bifunctional riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Nicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.707 |
| ZPR_3586 | ribB | ZPR_3586 | ZPR_2864 | Bifunctional riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Bifunctional protein: GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.999 |
| ZPR_3586 | ribH | ZPR_3586 | ZPR_1456 | Bifunctional riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Riboflavin synthase subunit beta; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.993 |
| ZPR_3587 | ZPR_3586 | ZPR_3587 | ZPR_3586 | Haloacid dehalogenase-like hydrolase. | Bifunctional riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.920 |
| ZPR_3587 | ZPR_3588 | ZPR_3587 | ZPR_3588 | Haloacid dehalogenase-like hydrolase. | Conserved hypothetical protein. | 0.732 |