| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ZPR_0032 | kmo | ZPR_0032 | ZPR_3758 | Protein containing methyltransferase domain. | Kynurenine-3-monooxygenase-like protein; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily. | 0.736 |
| ZPR_0192 | ZPR_4295 | ZPR_0192 | ZPR_4295 | Tryptophan 2,3-dioxygenase. | N-formylkynurenine (aryl-) formamidase. | 0.761 |
| ZPR_0192 | kmo | ZPR_0192 | ZPR_3758 | Tryptophan 2,3-dioxygenase. | Kynurenine-3-monooxygenase-like protein; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily. | 0.789 |
| ZPR_0192 | kynU | ZPR_0192 | ZPR_3767 | Tryptophan 2,3-dioxygenase. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.992 |
| ZPR_0192 | nbaC | ZPR_0192 | ZPR_0297 | Tryptophan 2,3-dioxygenase. | Putative 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. | 0.711 |
| ZPR_0586 | kmo | ZPR_0586 | ZPR_3758 | Cytochrome P450. | Kynurenine-3-monooxygenase-like protein; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily. | 0.682 |
| ZPR_0646 | kmo | ZPR_0646 | ZPR_3758 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase; Belongs to the HMG-CoA reductase family. | Kynurenine-3-monooxygenase-like protein; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily. | 0.676 |
| ZPR_1138 | kmo | ZPR_1138 | ZPR_3758 | Methyltransferase. | Kynurenine-3-monooxygenase-like protein; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily. | 0.672 |
| ZPR_1140 | kmo | ZPR_1140 | ZPR_3758 | Methyltransferase. | Kynurenine-3-monooxygenase-like protein; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily. | 0.672 |
| ZPR_3345 | kmo | ZPR_3345 | ZPR_3758 | Fatty acid alpha hydroxylase, cytochrome P450. | Kynurenine-3-monooxygenase-like protein; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily. | 0.682 |
| ZPR_4295 | ZPR_0192 | ZPR_4295 | ZPR_0192 | N-formylkynurenine (aryl-) formamidase. | Tryptophan 2,3-dioxygenase. | 0.761 |
| ZPR_4295 | kmo | ZPR_4295 | ZPR_3758 | N-formylkynurenine (aryl-) formamidase. | Kynurenine-3-monooxygenase-like protein; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily. | 0.697 |
| ZPR_4295 | kynU | ZPR_4295 | ZPR_3767 | N-formylkynurenine (aryl-) formamidase. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.850 |
| ZPR_4295 | nbaC | ZPR_4295 | ZPR_0297 | N-formylkynurenine (aryl-) formamidase. | Putative 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. | 0.596 |
| kmo | ZPR_0032 | ZPR_3758 | ZPR_0032 | Kynurenine-3-monooxygenase-like protein; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily. | Protein containing methyltransferase domain. | 0.736 |
| kmo | ZPR_0192 | ZPR_3758 | ZPR_0192 | Kynurenine-3-monooxygenase-like protein; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily. | Tryptophan 2,3-dioxygenase. | 0.789 |
| kmo | ZPR_0586 | ZPR_3758 | ZPR_0586 | Kynurenine-3-monooxygenase-like protein; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily. | Cytochrome P450. | 0.682 |
| kmo | ZPR_0646 | ZPR_3758 | ZPR_0646 | Kynurenine-3-monooxygenase-like protein; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily. | 3-hydroxy-3-methylglutaryl-coenzyme A reductase; Belongs to the HMG-CoA reductase family. | 0.676 |
| kmo | ZPR_1138 | ZPR_3758 | ZPR_1138 | Kynurenine-3-monooxygenase-like protein; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily. | Methyltransferase. | 0.672 |
| kmo | ZPR_1140 | ZPR_3758 | ZPR_1140 | Kynurenine-3-monooxygenase-like protein; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily. | Methyltransferase. | 0.672 |