| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ZPR_0192 | ZPR_4198 | ZPR_0192 | ZPR_4198 | Tryptophan 2,3-dioxygenase. | Putative cyclase. | 0.424 |
| ZPR_0192 | ZPR_4295 | ZPR_0192 | ZPR_4295 | Tryptophan 2,3-dioxygenase. | N-formylkynurenine (aryl-) formamidase. | 0.761 |
| ZPR_0192 | kmo | ZPR_0192 | ZPR_3758 | Tryptophan 2,3-dioxygenase. | Kynurenine-3-monooxygenase-like protein; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily. | 0.789 |
| ZPR_0192 | kynU | ZPR_0192 | ZPR_3767 | Tryptophan 2,3-dioxygenase. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.992 |
| ZPR_0192 | nbaC | ZPR_0192 | ZPR_0297 | Tryptophan 2,3-dioxygenase. | Putative 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. | 0.711 |
| ZPR_0374 | ZPR_3145 | ZPR_0374 | ZPR_3145 | Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide. | Catalase. | 0.945 |
| ZPR_0374 | katG | ZPR_0374 | ZPR_3703 | Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide. | Bifunctional heme catalase-peroxidase; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily. | 0.933 |
| ZPR_0374 | kynU | ZPR_0374 | ZPR_3767 | Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.904 |
| ZPR_0374 | nbaC | ZPR_0374 | ZPR_0297 | Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide. | Putative 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. | 0.900 |
| ZPR_3145 | ZPR_0374 | ZPR_3145 | ZPR_0374 | Catalase. | Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide. | 0.945 |
| ZPR_3145 | katG | ZPR_3145 | ZPR_3703 | Catalase. | Bifunctional heme catalase-peroxidase; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily. | 0.915 |
| ZPR_3145 | kynU | ZPR_3145 | ZPR_3767 | Catalase. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.904 |
| ZPR_3145 | nbaC | ZPR_3145 | ZPR_0297 | Catalase. | Putative 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. | 0.900 |
| ZPR_3766 | kynU | ZPR_3766 | ZPR_3767 | Hypothetical protein. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.752 |
| ZPR_3923 | kynU | ZPR_3923 | ZPR_3767 | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.681 |
| ZPR_4198 | ZPR_0192 | ZPR_4198 | ZPR_0192 | Putative cyclase. | Tryptophan 2,3-dioxygenase. | 0.424 |
| ZPR_4198 | kynU | ZPR_4198 | ZPR_3767 | Putative cyclase. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.730 |
| ZPR_4295 | ZPR_0192 | ZPR_4295 | ZPR_0192 | N-formylkynurenine (aryl-) formamidase. | Tryptophan 2,3-dioxygenase. | 0.761 |
| ZPR_4295 | kmo | ZPR_4295 | ZPR_3758 | N-formylkynurenine (aryl-) formamidase. | Kynurenine-3-monooxygenase-like protein; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily. | 0.697 |
| ZPR_4295 | kynU | ZPR_4295 | ZPR_3767 | N-formylkynurenine (aryl-) formamidase. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.850 |