Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (365 aa)    
Predicted Functional Partners:
bioD
Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.
 
 
 0.998
ZPR_4501
Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.992
ZPR_4503
Putative 8-amino-7-oxononanoate synthase.
  
 0.972
ZPR_0810
biotin--acetyl-CoA-carboxylase ligase.
  
 
 0.934
ZPR_4497
Conserved hypothetical protein.
       0.785
ZPR_4498
Conserved hypothetical protein.
       0.785
ZPR_3450
class-I/II aminotransferase.
 
  
 0.717
ZPR_4500
3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
  
 0.695
kbl
2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
  
  
 0.645
ZPR_1856
Ornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 
  
 0.645
Your Current Organism:
Zunongwangia profunda
NCBI taxonomy Id: 655815
Other names: Z. profunda SM-A87, Zunongwangia profunda SM-A87, Zunongwangia profunda str. SM-A87, Zunongwangia profunda strain SM-A87
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