| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ZPR_2344 | ZPR_4501 | ZPR_2344 | ZPR_4501 | Aminocarboxylic acid CoA-ligase. | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.652 |
| ZPR_2344 | bioB | ZPR_2344 | ZPR_4499 | Aminocarboxylic acid CoA-ligase. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.645 |
| ZPR_2344 | bioD | ZPR_2344 | ZPR_4502 | Aminocarboxylic acid CoA-ligase. | Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.739 |
| ZPR_2344 | kbl | ZPR_2344 | ZPR_0271 | Aminocarboxylic acid CoA-ligase. | 2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. | 0.921 |
| ZPR_3450 | ZPR_4501 | ZPR_3450 | ZPR_4501 | class-I/II aminotransferase. | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.659 |
| ZPR_3450 | bioB | ZPR_3450 | ZPR_4499 | class-I/II aminotransferase. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.717 |
| ZPR_3450 | bioD | ZPR_3450 | ZPR_4502 | class-I/II aminotransferase. | Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.740 |
| ZPR_3586 | ZPR_4501 | ZPR_3586 | ZPR_4501 | Bifunctional riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.418 |
| ZPR_3586 | bioB | ZPR_3586 | ZPR_4499 | Bifunctional riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.414 |
| ZPR_3586 | bioD | ZPR_3586 | ZPR_4502 | Bifunctional riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.419 |
| ZPR_4497 | ZPR_4500 | ZPR_4497 | ZPR_4500 | Conserved hypothetical protein. | 3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | 0.468 |
| ZPR_4497 | ZPR_4501 | ZPR_4497 | ZPR_4501 | Conserved hypothetical protein. | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.558 |
| ZPR_4497 | bioB | ZPR_4497 | ZPR_4499 | Conserved hypothetical protein. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.785 |
| ZPR_4500 | ZPR_4497 | ZPR_4500 | ZPR_4497 | 3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | Conserved hypothetical protein. | 0.468 |
| ZPR_4500 | ZPR_4501 | ZPR_4500 | ZPR_4501 | 3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.821 |
| ZPR_4500 | ZPR_4503 | ZPR_4500 | ZPR_4503 | 3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | Putative 8-amino-7-oxononanoate synthase. | 0.593 |
| ZPR_4500 | bioB | ZPR_4500 | ZPR_4499 | 3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.695 |
| ZPR_4500 | bioD | ZPR_4500 | ZPR_4502 | 3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.802 |
| ZPR_4501 | ZPR_2344 | ZPR_4501 | ZPR_2344 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Aminocarboxylic acid CoA-ligase. | 0.652 |
| ZPR_4501 | ZPR_3450 | ZPR_4501 | ZPR_3450 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | class-I/II aminotransferase. | 0.659 |