node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FEN1 | MAC_00291 | E9DV79 | E9DRC2 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Von Willebrand domain containing protein. | 0.694 |
FEN1 | MAC_00382 | E9DV79 | E9DRL3 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Ku70/Ku80 domain & Ku-core domain containing protein. | 0.703 |
FEN1 | MAC_02547 | E9DV79 | E9DY49 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Ubiquitin ligase subunit CulD; Belongs to the cullin family. | 0.590 |
FEN1 | MAC_02772 | E9DV79 | E9DYS4 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA repair protein rad14. | 0.821 |
FEN1 | MAC_06654 | E9DV79 | E9E9V6 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Acriflavine sensitivity control protein acr-2. | 0.486 |
FEN1 | MAC_07157 | E9DV79 | E9EBA9 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Ubiquitin-like modifier SUMO, putative. | 0.460 |
FEN1 | MAC_09356 | E9DV79 | E9EHK8 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Cyclin_C_2 domain-containing protein. | 0.633 |
MAC_00291 | FEN1 | E9DRC2 | E9DV79 | Von Willebrand domain containing protein. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.694 |
MAC_00291 | MAC_00382 | E9DRC2 | E9DRL3 | Von Willebrand domain containing protein. | Ku70/Ku80 domain & Ku-core domain containing protein. | 0.585 |
MAC_00291 | MAC_01167 | E9DRC2 | E9DU69 | Von Willebrand domain containing protein. | Ubiquitin-conjugating enzyme E2-18 kDa; Belongs to the ubiquitin-conjugating enzyme family. | 0.609 |
MAC_00291 | MAC_01424 | E9DRC2 | E9DV34 | Von Willebrand domain containing protein. | Acriflavine sensitivity control protein acr-2. | 0.592 |
MAC_00291 | MAC_02547 | E9DRC2 | E9DY49 | Von Willebrand domain containing protein. | Ubiquitin ligase subunit CulD; Belongs to the cullin family. | 0.602 |
MAC_00291 | MAC_02772 | E9DRC2 | E9DYS4 | Von Willebrand domain containing protein. | DNA repair protein rad14. | 0.590 |
MAC_00291 | MAC_06653 | E9DRC2 | E9E9V5 | Von Willebrand domain containing protein. | Poly(ADP-ribose) glycohydrolase isoform. | 0.592 |
MAC_00291 | MAC_06654 | E9DRC2 | E9E9V6 | Von Willebrand domain containing protein. | Acriflavine sensitivity control protein acr-2. | 0.592 |
MAC_00291 | MAC_07157 | E9DRC2 | E9EBA9 | Von Willebrand domain containing protein. | Ubiquitin-like modifier SUMO, putative. | 0.624 |
MAC_00291 | MAC_09356 | E9DRC2 | E9EHK8 | Von Willebrand domain containing protein. | Cyclin_C_2 domain-containing protein. | 0.584 |
MAC_00382 | FEN1 | E9DRL3 | E9DV79 | Ku70/Ku80 domain & Ku-core domain containing protein. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.703 |
MAC_00382 | MAC_00291 | E9DRL3 | E9DRC2 | Ku70/Ku80 domain & Ku-core domain containing protein. | Von Willebrand domain containing protein. | 0.585 |
MAC_00382 | MAC_02772 | E9DRL3 | E9DYS4 | Ku70/Ku80 domain & Ku-core domain containing protein. | DNA repair protein rad14. | 0.632 |