STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAC_00291Von Willebrand domain containing protein. (723 aa)    
Predicted Functional Partners:
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
   
 0.694
MAC_07157
Ubiquitin-like modifier SUMO, putative.
    
 0.624
MAC_01167
Ubiquitin-conjugating enzyme E2-18 kDa; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.609
MAC_02547
Ubiquitin ligase subunit CulD; Belongs to the cullin family.
    
 0.602
MAC_01424
Acriflavine sensitivity control protein acr-2.
    
 0.592
MAC_06653
Poly(ADP-ribose) glycohydrolase isoform.
    
 0.592
MAC_06654
Acriflavine sensitivity control protein acr-2.
    
 0.592
MAC_02772
DNA repair protein rad14.
     
 0.590
MAC_00382
Ku70/Ku80 domain & Ku-core domain containing protein.
   
 
 0.585
MAC_09356
Cyclin_C_2 domain-containing protein.
     
 0.584
Your Current Organism:
Metarhizium acridum
NCBI taxonomy Id: 655827
Other names: M. acridum CQMa 102, Metarhizium acridum CQMa 102, Metarhizium anisopliae var. acridum CQMa 102
Server load: low (12%) [HD]