node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DRE2 | MAC_00439 | E9DX80 | E9DRS0 | Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...] | Uncharacterized protein; Belongs to the BolA/IbaG family. | 0.697 |
DRE2 | MAC_02862 | E9DX80 | E9DZ14 | Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...] | Glutaredoxin; Belongs to the glutaredoxin family. Monothiol subfamily. | 0.892 |
DRE2 | MAC_04646 | E9DX80 | E9E448 | Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...] | BolA domain-containing protein; Belongs to the BolA/IbaG family. | 0.752 |
DRE2 | MAC_05528 | E9DX80 | E9E6N0 | Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...] | BolA-like family protein; Belongs to the BolA/IbaG family. | 0.827 |
DRE2 | MAC_05671 | E9DX80 | E9E6X5 | Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...] | NifU-like protein. | 0.517 |
DRE2 | MAC_06086 | E9DX80 | E9E888 | Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...] | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.633 |
DRE2 | MAC_07153 | E9DX80 | E9EBA5 | Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...] | Monothiol glutaredoxin-4. | 0.961 |
MAC_00439 | DRE2 | E9DRS0 | E9DX80 | Uncharacterized protein; Belongs to the BolA/IbaG family. | Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...] | 0.697 |
MAC_00439 | MAC_02862 | E9DRS0 | E9DZ14 | Uncharacterized protein; Belongs to the BolA/IbaG family. | Glutaredoxin; Belongs to the glutaredoxin family. Monothiol subfamily. | 0.782 |
MAC_00439 | MAC_03133 | E9DRS0 | E9DZT5 | Uncharacterized protein; Belongs to the BolA/IbaG family. | NADH-ubiquinone oxidoreductase B14 subunit. | 0.846 |
MAC_00439 | MAC_04646 | E9DRS0 | E9E448 | Uncharacterized protein; Belongs to the BolA/IbaG family. | BolA domain-containing protein; Belongs to the BolA/IbaG family. | 0.646 |
MAC_00439 | MAC_05528 | E9DRS0 | E9E6N0 | Uncharacterized protein; Belongs to the BolA/IbaG family. | BolA-like family protein; Belongs to the BolA/IbaG family. | 0.988 |
MAC_00439 | MAC_05671 | E9DRS0 | E9E6X5 | Uncharacterized protein; Belongs to the BolA/IbaG family. | NifU-like protein. | 0.667 |
MAC_00439 | MAC_06086 | E9DRS0 | E9E888 | Uncharacterized protein; Belongs to the BolA/IbaG family. | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.574 |
MAC_00439 | MAC_06781 | E9DRS0 | E9EA83 | Uncharacterized protein; Belongs to the BolA/IbaG family. | Uncharacterized protein. | 0.608 |
MAC_00439 | MAC_06793 | E9DRS0 | E9EA94 | Uncharacterized protein; Belongs to the BolA/IbaG family. | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. | 0.639 |
MAC_00439 | MAC_07153 | E9DRS0 | E9EBA5 | Uncharacterized protein; Belongs to the BolA/IbaG family. | Monothiol glutaredoxin-4. | 0.785 |
MAC_02862 | DRE2 | E9DZ14 | E9DX80 | Glutaredoxin; Belongs to the glutaredoxin family. Monothiol subfamily. | Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...] | 0.892 |
MAC_02862 | MAC_00439 | E9DZ14 | E9DRS0 | Glutaredoxin; Belongs to the glutaredoxin family. Monothiol subfamily. | Uncharacterized protein; Belongs to the BolA/IbaG family. | 0.782 |
MAC_02862 | MAC_04646 | E9DZ14 | E9E448 | Glutaredoxin; Belongs to the glutaredoxin family. Monothiol subfamily. | BolA domain-containing protein; Belongs to the BolA/IbaG family. | 0.849 |