STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAC_01025F-box and JmjC domain protein, putative. (463 aa)    
Predicted Functional Partners:
MAC_02515
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.804
MAC_09124
Histone H3; Belongs to the histone H3 family.
    
 0.756
MAC_08145
U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family.
    
 
 0.623
MAC_07885
DUF2236 domain-containing protein.
    
 0.603
MAC_01786
Transcription regulator BDF1, putative.
    
 
 0.538
MAC_08435
Putative Bromodomain testis-specific protein.
    
 
 0.538
MAC_09414
Jumonji domain containing 5.
      
 0.513
MAC_04053
PHD transcription factor.
      
 0.495
MAC_03648
Putative dock180 protein; Belongs to the DOCK family.
    
 
 0.453
MAC_05772
Putative regulator of deoxyribodipyrimidine photo-lyase PHR1.
      
 0.403
Your Current Organism:
Metarhizium acridum
NCBI taxonomy Id: 655827
Other names: M. acridum CQMa 102, Metarhizium acridum CQMa 102, Metarhizium anisopliae var. acridum CQMa 102
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.