STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAC_02487Ran exchange factor Prp20/Pim1, putative. (539 aa)    
Predicted Functional Partners:
MAC_05258
GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.
    
 0.877
MAC_06530
Ubiquitin-protein ligase (Hul4), putative.
 
  
 0.876
MAC_01141
Nucleoporin nsp1.
   
 0.838
MAC_00499
Importin subunit alpha; Belongs to the importin alpha family.
   
 
 0.765
MAC_02515
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
  0.626
MAC_00127
Histone H2A; Belongs to the histone H2A family.
    
 0.618
MAC_01640
Uncharacterized protein.
   
 0.515
MAC_01641
Ran/spi1 binding protein.
   
 0.515
MAC_09124
Histone H3; Belongs to the histone H3 family.
   
 0.506
MAC_03542
Small GTP-binding protein YPTI.
    
 
 0.503
Your Current Organism:
Metarhizium acridum
NCBI taxonomy Id: 655827
Other names: M. acridum CQMa 102, Metarhizium acridum CQMa 102, Metarhizium anisopliae var. acridum CQMa 102
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