STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAC_06398Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. (131 aa)    
Predicted Functional Partners:
MAC_05223
Actin.
    
 0.957
MAC_03937
Cytokinesis protein.
    
 0.902
MAC_07889
Adenylyl cyclase-associated protein; Belongs to the CAP family.
   
 0.896
MAC_04927
Actin-like protein (Centractin); Belongs to the actin family.
    
 0.883
MAC_07403
Morphogenesis protein (Msb1), putative.
    
 0.869
MAC_02284
Uncharacterized protein.
    
 0.826
MAC_03557
Actin-like protein 3; Belongs to the actin family.
   
 0.822
MAC_02843
Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.
   
 0.805
MAC_06228
Actin; Belongs to the actin family.
    
 0.801
MAC_09573
Cofilin, putative; Belongs to the actin-binding proteins ADF family.
   
 0.796
Your Current Organism:
Metarhizium acridum
NCBI taxonomy Id: 655827
Other names: M. acridum CQMa 102, Metarhizium acridum CQMa 102, Metarhizium anisopliae var. acridum CQMa 102
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.