STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAC_07722Putative nitrate assimilation regulatory protein nirA. (663 aa)    
Predicted Functional Partners:
MAC_00124
Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy.
   
 0.966
MAC_02566
Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...]
   
 0.957
MAC_05361
Autophagy-related protein 3.
   
 0.957
MAC_01142
ZZ type zinc finger domain-containing protein.
   
 0.931
MAC_06688
Autophagy related lipase.
   
 
 0.895
MAC_04998
Serine/threonine-protein kinase.
   
 0.885
MAC_09741
Calcium/calmodulin-dependent protein kinase.
   
 0.885
MAC_02739
Autophagy-related ubiquitin-like modifier atg-12.
   
 0.853
MAC_09129
Autophagy-related protein 18.
   
 0.850
MAC_07287
Autophagy-related protein 6.
    
 0.788
Your Current Organism:
Metarhizium acridum
NCBI taxonomy Id: 655827
Other names: M. acridum CQMa 102, Metarhizium acridum CQMa 102, Metarhizium anisopliae var. acridum CQMa 102
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.